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• Binding: Paperback

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Schaechter's Mechanisms of Microbial Disease provides students with a thorough understanding of microbial agents and the pathophysiology of microbial diseases. The text is universally praised for "telling the story of a pathogen" in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms, rather than forcing students to memorize isolated facts by rote. The table of contents is uniquely organized by microbial class and by organ system, making it equally at home in traditional and systems-based curricula. Case studies with problem-solving questions give students insight into clinical applications of microbiology, which is ideal for problem-based learning.

• Sales Rank: #48414 in Books
• Brand: Brand: Lippincott Williams Wilkins
• Published on: 2012-06-20
• Original language: English
• Number of items: 1
• Dimensions: 11.00" h x 8.50" w x 1.50" l, 4.40 pounds
• Binding: Paperback
• 848 pages

Features

• Used Book in Good Condition

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3 of 3 people found the following review helpful.
Terrific book, compact and easy to get through without sacrificing too much detail
By chefpalatini
My professors highly recommended this book, and I grudgingly bought it. I am really happy with it as it provides important context and explanation as well as interesting stories relating to the topic at hand while remaining compact and portable. For a textbook- it's fantastic. For lite evening reading... doable I guess.

1 of 1 people found the following review helpful.
Great book for serious studies
By Kelly
This is a great book for anyone seriously studying microbes! The chapters are short and readable and it is a valuable reference to hold on to long after a class is over. This is one of the few textbooks I don't regret spending money on.

0 of 0 people found the following review helpful.
Not a complete source for medical students.
By Amber R. Dubiel
The organization of this textbook is horrible, and I have found numerous important facts missing from the chapters. Examples: Quelling reaction is never stated in the entire textbook (used to diagnose strept pneumonia), and there is no mention in the entire textbook of Bacitracin sensitivity, even though it is used to differentiate Group A from group B streptococcus. Sadly my school has chosen this book to be my only source of information, which is now greatly lacking. I would highly recommend supplementing your readings with First Aid of the Basic Sciences if you are a medical student. I wish I would have realized how terrible of a book this was earlier on.

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Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been exploding. Inclusion of high-dimensional data and imaging techniques have become common practice, and statistical methods on how to analyse such data have been refined in this area. A compilation of statistical topics relevant to these new advances in cancer research, this third edition of Handbook of Statistics in Clinical Oncology focuses on the design and analysis of oncology clinical trials and translational research.

Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials, incorporating updates to all four parts:

• Phase I trials: Updated recommendations regarding the standard 3 + 3 and continual reassessment approaches, along with new chapters on phase 0 trials and phase I trial design for targeted agents.
• Phase II trials: Updates to current experience in single-arm and randomized phase II trial designs. New chapters include phase II designs with multiple strata and phase II/III designs.
• Phase III trials: Many new chapters include interim analyses and early stopping considerations, phase III trial designs for targeted agents and for testing the ability of markers, adaptive trial designs, cure rate survival models, statistical methods of imaging, as well as a thorough review of software for the design and analysis of clinical trials.
• Exploratory and high-dimensional data analyses: All chapters in this part have been thoroughly updated since the last edition. New chapters address methods for analyzing SNP data and for developing a score based on gene expression data. In addition, chapters on risk calculators and forensic bioinformatics have been added.

Accessible to statisticians and oncologists interested in clinical trial methodology, the book is a single-source collection of up-to-date statistical approaches to research in clinical oncology.

• Sales Rank: #1013420 in Books
• Published on: 2012-03-26
• Original language: English
• Number of items: 1
• Dimensions: 9.10" h x 1.70" w x 6.40" l, 2.25 pounds
• Binding: Hardcover
• 657 pages

Review

"A strength of the handbook is the large number of examples that are included in most chapters that expand on the theoretical basis underpinning the relevant methodology. Each chapter provides details of new developments in the specific methodology and provides a comprehensive list of references for the reader to seek further information when required. … The book contains a wealth of information about a wide range of statistical methodologies, some of which are not limited to clinical trials. … a valuable update to a resource that covers a comprehensive range of topics related to the design, analysis and interpretation of clinical trials in cancer research."
―Peter Baade, Australian & New Zealand Journal of Statistics, 2013

Praise for the Second Edition:
"The new topics and contributions in this edition include the recently developed tools for high-dimensional data and bioinformatics in clinical oncology research. A new section has been added emphasizing the importance and rapid developments of these topics over the 5 years since the publication of the first edition. Some of the original sections have been updated to include the state-of-the-art knowledge and tools in all topics. The end result is a comprehensive edited volume covering statistical and bioinformatics methods that provide the foundation for important research and clinical trials in cancer. … Like the last edition, this current edition will be an important addition to the libraries of all health research centers. The book will be prized as a reference book for biostatisticians, biomedical researchers, and oncologists for planning, conducting, analyzing, and interpreting cancer research."
―Journal of the American Statistical Association, Vol. 104, No. 487, September 2009

"This is a expanded and revised second edition of a text that was initially well received by the community. The book comprised of 33 chapters, grouped into 6 sections. … The text is extremely well referenced. The authorship represents the leaders in the field. A significant strength of this book is its example-driven approach to the ‘out-of-the-box’ but practical issues faced by those conducting cancer clinical trials. The book provides a critical assessment of the state of science through a thorough review of the methods, applications, and available resources. … a detailed and mostly comprehensive text on the topics of cancer clinical trial design, conduct, analysis, and interpretation."
―Daniel Sargent, Sumithra Mandrekar, and Ann Oberg, Mayo Clinic, Biometrics, December 2006

About the Author

John J. Crowley is president and CEO of Cancer Research and Biostatistics (CRAB), Seattle, Washington, director of the SWOG Statistical Center, and a faculty member at the Fred Hutchinson Cancer Research Center. The author or coauthor of more than 350 refereed articles, book chapters, and other publications, Dr. Crowley is a fellow of the American Statistical Association and the American Association for the Advancement of Science and a member of the International Biometrics Society, the American Society for Clinical Oncology, and the International Association for the Study of Lung Cancer. He received his BA (1968) from Pomona College, Claremont, California, and his MS (1970) and PhD (1973) in biomathematics from the University of Washington, Seattle.

Antje Hoering, PhD, is a senior biostatistician at Cancer Research and Biostatistics (CRAB), Seattle, Washington. She is also an affiliate faculty member in the Department of Biostatistics at the University of Washington and an affiliate investigator at the Fred Hutchinson Cancer Research Center. Dr. Hoering is the lead statistician of the SWOG Myeloma Committee, the SWOG Early Therapeutics Subcommittee, and the Stand Up To Cancer, Pancreatic Dream Team. She is the coordinating statistician for the Myeloma Institute for Research and Therapy, the International Myeloma Committee, and the Pancreatic Cancer Research Team. She serves as a consultant on a variety of industry-sponsored studies and has been the biostatistics representative on two Type B meetings with the FDA. She is member of the American Statistical Association, the International Biometrics Society, and the International Myeloma Society. She received her BS (1985) from the University of Tubingen, Germany, her MS (1988) in physics from Oregon State University, Corvallis, and her PhD (1991) in physics from the Max Planck Institute for Theoretical Nuclear Physics, Heidelberg, Germany. She transitioned into biostatistics with a three-year NRSA postdoctoral fellowship with the Department of Biostatistics at the University of Washington and the Fred Hutchinson Cancer Research Center.

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• Published on: 1995
• Binding: Paperback

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• Sales Rank: #5622717 in Books
• Brand: Brand: Mercer University Press
• Published on: 1996-06-01
• Original language: English
• Number of items: 1
• Dimensions: 9.02" h x 1.50" w x 5.98" l, 2.21 pounds
• Binding: Hardcover
• 624 pages

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4 of 4 people found the following review helpful.
A Must for Biblical students, scholars and veracity seekers
By fdoamerica
Life has its mystery, which often baffles and challenges those that seek its secrets. For millenniums Old Testament wisdom literature has given reflections and observations about the reality of life. Most of the teachings from these texts comes from "experiential wisdom," wise words based on encounters with life, not theory. Wisdom literature excels in bestowing to the reader instructions on how to live, find happiness and prosper. They are the world's first "How To" books.
One of the leading specialists in Old Testament Wisdom literature is James L. Crenshaw, Professor of Old Testament at Duke University Divinity School. For more than 30 years he has written provocative essays on Ecclesiastes, Proverbs and Job. In "Urgent Advice and Probing Questions," you will find 37 essays that contain valuable and insightful information. This should not be a `one sitting' reading, for the depth and discrimination used in examining these texts requires selective reading. However, for those Biblical students, scholars and veracity seekers, "Urgent Advice and Probing Questions" will be a book that you will return to over and over. Highly Recommended

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• Sales Rank: #4759122 in Books
• Published on: 2006-04-30
• Original language: Spanish
• Number of items: 1
• Dimensions: 9.00" h x 6.00" w x .75" l,
• Binding: Paperback
• 268 pages

Most helpful customer reviews

0 of 0 people found the following review helpful.
Buenísimo
By Dionisio Otarola
Este es uno de esos libros que está lleno de pensamientos profundos en un solo párrafo. Sabio y práctico. También es de fácil lectura.

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Los Siete Niveles De La Intimidad/ the Seven Levels of Intimacy: El Arte De Amar Y La Alegria De Ser Amado / the Art of Loving and the Joy PDF
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• Published on: 1983
• Binding: Paperback

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